MNPROtein - Hamster

Secure definitive results using MNPROtein as a substrate for real-time quaking-induced conversion (RT-QuIC) assays of critical proteopathies, including Chronic Wasting Disease. Produced at the University of Minnesota, MNPROtein consists of a recombinant, truncated prion protein derived from Syrian hamster (amino acids 90-231 Syrian Hamster), and is externally audited for quality. Protein concentration is ensured by A280 with a mass attenuation coefficient of 1.4 and is purified with nickel-affinity chromatography. Each production batch is then internally validated to ensure rigorous quality control before distribution.

Our MNPRO research team performs thousands of RT-QuIC reactions weekly and we use the same MNPROtein substrate sold to consumers, thus helping to ensure real-time reproducibility and quality assurance. We additionally partner with external collaborators on a variety of RT-QuIC research projects that leverage MNPROtein, with peer-reviewed publications growing rapidly.

Sold per 96-well plate unit at approximately 0.5-1.0 mg/mL.

Due to high demand, the sale of MNPROtein product is currently being transferred to Priogen Corp.

MNPRO is in the process of moving this product offering to the University of Minnesota spin-out company Priogen Corp to meet the increasing demand, enhance quality controls, and provide additional customer services. The substrate will remain unchanged, identical to what was available through MNPRO.

MNPROtein is expected to be available through Priogen Corp in early February. A link will be provided here, and Priogen will email current customers. Please contact sales@priogen.bio with any questions.